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Abstract #3039

Modelling the Brain Functional Difference of Movie Watching and Resting State with Autoencoder

Yifei Sun1, Fernando Calamante1,2,3, and Jinglei Lv1,2
1School of Biomedical Engineering, University of Sydney, Sydney, Australia, 2Brain and Mind Centre, University of Sydney, Sydney, Australia, 3Sydney Imaging, University of Sydney, Sydney, Australia


The human brain is a complex dynamic system. Understanding the functional difference of the brain between the resting state and performing tasks helps to decipher the functional brain architecture. In this work, we trained an autoencoder to optimally reconstruct the resting state fMRI (rs-fMRI) data of 50 subjects, and this model was subsequently used to reconstruct the movie watching fMRI (mw-fMRI) data of the same subjects. We have compared the reconstruction error between movie watching and resting state, and significant regional functional differences were found.

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