We determined MWF derived from QPM-relaxation parameters using quadratic polynomial approximation. Two types of myelin imaging were generated; MWF derived from multi-echo gradient-echo and R1·R2* map derived from QPM, which were standardized from twelve healthy volunteers to MNI. As a result, the relationship between MWF and R1·R2* values on the white matter region strongly correlated with a quadratic polynomial approximation (R2 = 0.991). Using acquired quadratic polynomial approximation, the R1·R2* map was converted to MWF. Our MWF map derived from QPM can dramatically improve image quality when compared to the general MWF.
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