Quantification of bone marrow component change using chemical shift-encoded MRI in Ankylosing Spondylitis patients in different stages
Liping Ma1, Long Qian2, Zhibin Zeng1, Cuiyun Sheng1, Yang Wang1, Gen Li3, and Gaoyun Wu1
1Department of Radiology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China, 2MR Research, GE Healthcare, Bejing, China, 3Department of Emergency, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China
Quantification of fat fraction (FF) and R2* in areas of bone marrow edema (BME) and fat metaplasia in different stages Ankylosing Spondylitis (AS). 75 AS in 3 different stage (early acute group, late acute group, stable group), 42 BME and 39 fat metaplasia were detected. Difference of FF, R2* in BME and fat metaplasia in different stages were compared and relationship between FF and R2* were analyzed. Result showed R2* in fat metaplasia, but not in BME, is significantly negative with FF. FF and R2* measurements can quantitatively analyze bone marrow component change in AS.
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