Abstract #3082

Quantification of bone marrow component change using chemical shift-encoded MRI in Ankylosing Spondylitis patients in different stages

Liping Ma¹, Long Qian², Zhibin Zeng¹, Cuiyun Sheng¹, Yang Wang¹, Gen Li³, and Gaoyun Wu¹

¹Department of Radiology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China, ²MR Research, GE Healthcare, Bejing, China, ³Department of Emergency, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China

Synopsis

Quantification of fat fraction (FF) and R2* in areas of bone marrow edema (BME) and fat metaplasia in different stages Ankylosing Spondylitis (AS). 75 AS in 3 different stage (early acute group, late acute group, stable group), 42 BME and 39 fat metaplasia were detected. Difference of FF, R2* in BME and fat metaplasia in different stages were compared and relationship between FF and R2* were analyzed. Result showed R2* in fat metaplasia, but not in BME, is significantly negative with FF. FF and R2* measurements can quantitatively analyze bone marrow component change in AS.

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