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Abstract #3084

Repeatability and feasibility of amide proton transfer imaging in musculoskeletal tumors

Ming Wen1, Yujin Zhang1, Jianling Cui1, and Zhiwei Shen2
1The Third Hospital, Hebei Medical University, Shijiazhuang, China, 2Philips healthcare,Beijing,China, Beijing, China


Amide proton transfer (APT) imaging is a noninvasive emerging molecular MRI technique. Currently, APT was mainly used for the diagnosis, classify and recurrence prediction of head glioma. The application in other tissue such as musculoskeletal disease is limited. The feasibility and the repeatability of APT imaging in body or other tissues is necessary for its clinical practice. In this study, we explorer the scan-rescan repeatability of APT imaging in musculoskeletal (MSK) tumor on a clinical 3.0T MR scanner, and further to differentiate malignant from benign solid tumors in the study.

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