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Abstract #3091

The Trajectory of Knee Structures Before The Onset of Rheumatoid Arthritis: A 4-Year Longitudinal Magnetic Resonance Imaging Study

Qiaoling Zhong1, Xintao Zhang1, Zhongping Zhang2, and Xiaodong Zhang1
1Department of Medical Imaging, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China, 2Philips Healthcare, Guangzhou, China

Synopsis

The knee joint is one of the most commonly affected large joint in rheumatoid arthritis (RA). Its progression often causes joint destruction and deformity. The cartilage injury, bone marrow lesions and synovitis scores of the knees at baseline, P-1 (1 year prior to P0), and P0 (time of onset of RA) were evaluated using the MOAKS score. The generalized estimation equation (GEE) was used to compare the MR scores of knee joints at three time points to observe the longitudinal changes. The changes of bone marrow lesions and synovitis scores in knee joints were significant before the occurrence of RA.

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