Abstract #3092

Evaluation of Multimodal MRI in RA Efficacy Based on Quantitative Bone Marrow Edema

Wenzhao Yuan¹, Yi Dai², Yiwu Lei³, Fang Qin⁴, Huiting Zhang⁵, Zisan Zeng³, and Liling Long¹

¹The First Affiliated Hospital of Guangxi Medical University, Nanning, China, ²Radiology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China, ³Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China, ⁴Rheumatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China, ⁵Siemens Healthcare Ltd., Wuhan, China

Synopsis

This study evaluated the efficacy of MRI bone marrow edema imaging for rheumatoid arthritis (RA). Wrist joints of RA patients were examined at baseline and follow-up with T1 mapping, T2 mapping and IVIM, and their clinical indicator DAS28-ESR was also collected. Results showed that the changes of both T1 and D values had statistically positive correlations with DAS28-ESR. And the results showed that T1 and D values of bone marrow edema area in lunate bone, triangle bone and capitate bone can significantly reflect the curative effect of RA, and the change rate of T1 can predict the curative effect.

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