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Abstract #3109

Preliminary study of various models of DWI and diffusion kurtosis imaging on differential diagnosis of spinal metastase and chordoma

Jiahui Zhang1,2, Qizheng Wang2, and Ning Lang2
1Department of Radiology, Peking Union Medical College Hospital, Beijing, China, 2Peking University Third Hospital, Beijing, China


Metastases and chordoma are both malignant tumors. When the manifestations are not typical, the two are prone to misdiagnosis. DWI using a biexponential model measured ADC, D, D*, and f. DWI using a stretched-exponential model obtained DDC, and α. DKI derived MD and MK. The monoexponential, biexponential, and stretched-exponential models of DWI and DKI have differential diagnostic value for spinal metastases and chordoma. Among the single parameter values, the D value has the highest AUC. Combining the values of three parameters (D, f, and α) can significantly improve the diagnostic efficiency of identifying spinal metastases and chordoma.

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