Meeting Banner
Abstract #3108

Exercise-induced muscle hyperemia as quantified by a BOLD modelling approach

Yujie Wang1,2, Christopher J. Hanrahan3, and Jeff L. Zhang1
1Vascular and Physiologic Imaging Research (VPIR) Lab, School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, 2School of Life Science and Technology, ShanghaiTech University, Shanghai, China, 3Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States


Muscle hyperemia after exercise is a physiologic phenomenon that could reflect muscle function and performance. For a group of human subjects, we performed dynamic BOLD scan of calf muscles immediately after in-scanner plantar flexion. To analyze the dynamic data, a kinetic model of deoxy-hemoglobin (dHb) was proposed, with exponentially decayed perfusion as determinant. A hyperemia index (HI) was defined based on the estimated perfusion parameters, and was compared to muscle perfusion measured by DCE scans. In conclusion, we proposed a quantitative model for analyzing post-exercise muscle BOLD data, and the new parameter “hyperemia index”.

This abstract and the presentation materials are available to members only; a login is required.

Join Here