Abstract #3111

Intravoxel incoherent motion imaging of masticatory muscles in patients with head and neck cancer

Chia-Wei Lin¹, Kai-Lun Cheng², Hsueh-Ju Lu³, Ying-Hsiang Chou^1,4, Yeu-Sheng Tyan^1,2, and Ping-Huei Tsai^1,2

¹Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan, ²Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan, ³Division of Medical Oncology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan, ⁴Department of Radiation Oncology, Chung Shan Medical University Hospital, Taichung, Taiwan

Synopsis

Head and Neck Cancer (HNC) is one of the most common cancers worldwide. Although skeletal muscle depletion or muscle dysfunction is associated with cancer progression, changes in masticatory muscle diffusion and perfusion in HNC are still unclear. This study aims to assess the masticatory muscle perfusion and diffusion in HNC using intravoxel incoherent motion (IVIM) imaging. Our preliminary result indicated the normalized D* values in masticatory muscles were significantly lower in HNC patients than that in controls, suggesting the possibility of reduced masticatory muscle perfusion in HNC.

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