Intravoxel incoherent motion imaging of masticatory muscles in patients with head and neck cancer
Chia-Wei Lin1, Kai-Lun Cheng2, Hsueh-Ju Lu3, Ying-Hsiang Chou1,4, Yeu-Sheng Tyan1,2, and Ping-Huei Tsai1,2
1Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan, 2Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan, 3Division of Medical Oncology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan, 4Department of Radiation Oncology, Chung Shan Medical University Hospital, Taichung, Taiwan
Head and Neck Cancer (HNC) is one of the most common cancers worldwide. Although skeletal muscle depletion or muscle dysfunction is associated with cancer progression, changes in masticatory muscle diffusion and perfusion in HNC are still unclear. This study aims to assess the masticatory muscle perfusion and diffusion in HNC using intravoxel incoherent motion (IVIM) imaging. Our preliminary result indicated the normalized D* values in masticatory muscles were significantly lower in HNC patients than that in controls, suggesting the possibility of reduced masticatory muscle perfusion in HNC.
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