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Abstract #3123

Regional comparison of brain standardized uptake values in FBPA PET-MR with FBPA PET-CT

Chien-Ying Lee1,2, Chia-Wei Li3, Chien-Yuan Lin3, Wen-sheng Huang4, and Ko-Han Lin1
1Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, 2Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 3GE Healthcare, Taipei, Taiwan, 4Department of Nuclear Medicine, Taipei Medical University Hospital, Taipei, Taiwan


18F-fluoro-Boronophenylalanine (FBPA) Positron emission tomography (PET) plays a crucial role for patient selection prior to boron neutron capture therapy. As integrated PET-MR is being used frequently in clinical research and routine, this study aimed to compare regional difference of brain standard uptake values on the PET quantification accuracy in FBPA PET-CT and PET-MR among lesions and normal tissues. Compared to SUVR in PET-CT, PET-MR data showed significant lower SUVR in lesion regions, while no significance was observed in the normal tissue regions. The result of this study may accelerate the routine use of PET-MR in tumoral quantification before BNCT.

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