We explored the applied value of multi-mode MR imaging technology, including diffusion kurtosis imaging (DKI), arterial spin labeling (ASL) and 1H-MRS, in glioma tumor invasion boundary. Results showed mean kurtosis from DKI and apparent diffusion coefficient had the highest diagnostic efficiency between high-grade (HGG) and low-grade gliomas (LGG). There were significant differences in CHO/Cr and NAA/Cr from 1H-MRS between the solid area and the proximal peritumoral edema area (PEA), and CHO/Cr and NAA/Cr in different PEA of LGG or HGG. PEA within 1cm around the solid area is recommended to be resected to decrease recurrence rate.
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