APT imaging and its derived metric maps were applied to identify molecular subgroups of medulloblastoma for the first time. Thirty-eight newly-diagnosed pediatric patients with medulloblastoma were enrolled in this study and scanned on a 3T scanner. We implemented a radiomic analysis of the APT-related metric maps, with initial regions of interest delineated by an experienced radiologist and then shrunk automatically. After feature extraction and selection, five different classifiers were tested with both single-metric and multi-metric maps. We successfully established predictive models to differentiate the subgroups of medulloblastoma with good accuracy of 0.754.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords