Abstract #3136

Characterizing meningioma subtypes using MRI-cytometry

Ying-Hua Chu¹, Yifan Yuan², Xueying Zhao³, He Wang^3,4, Thorsten Feiweier⁵, and Yi-Cheng Hsu¹

¹Siemens Healthineers Ltd., Shanghai, China, ²Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China, ³Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ⁴Human Phenome Institute, Fudan University, Shanghai, China, ⁵Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

We used MRI-cytometry to estimate the mean cell diameter and intracellular volume of tumors of the meningioma subtype classification. We found cell size and intracellular volume to be very different between the three meningioma subtypes in this preliminary study. Our results reflected high collagen volume among the extracellular space in fibrous meningioma. We plan to scan more patients in the future to find a useful biomarker using MRI-cytometry.

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