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Abstract #3155

Structural connectivity abnormality in trigeminal neuralgia with pain relief using graph theory analysis

shanshan Shen1, shuqian Zhang1, yingmin Chen1, and Lizhi Xie2
1Hebei General Hospital, Shijiazhuang, China, 2GE Healthcare, Shijiazhuang, China


Trigeminal neuralgia (TN) characterized by recurring paroxysmal pain, severely affects the quality of life (QoL) of patients. In this study, we compared brain network frame remodeling in TN patients before and after percutaneous micro-balloon compression (PMC) operation with healthy controls (HCs) using graph theory analysis. Both TN pre-treatment patients (Pre) and HCs exhibited small-world network organization. Pre TN patients had abnormal global network construction, Pos recovered, but in local network index increased. Graph theory analysis could be a useful method to detect instant change after operation.

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