Two different T1 mapping sequences, based on the inversion recovery SNAPSHOT-FLASH sequence (LLIR-T1) and on B1 inhomogeneity-corrected variable flip angle (VFA-T1) acquisitions, were compared in a clinical setting. Results showed that the LLIR-T1 method had better image quality, and higher contrast between tumor and healthy liver tissue.c had a strong correlation with VFA-T1 method whether at different time point or regions. But LLIR-T1 had lower T1 in healthy liver lobe and higher T1 in tumor compared with VFA-T1.
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