Abstract #3209
Modular Graphene Quantum Dot Nano-transformers: An Efficient and Versatile Vehicle for Localized Tumor Imaging and Treatment
Yuqi Yang1, Baolong Wang1, and Xin Zhou1
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences–Wuhan National Laboratory for Optoelectronics, Wuhan, China
Synopsis
A versatile nano-vehicle, quantum dots nano-transformers, smartly transforms its shape in acidic tumor microenvironment to prolong the tumor retention, and then disassembles and releases the encapsulated photosensitizers to “turn on” the imaging contrast. The total drug dose in repeated photodynamic therapy is reduced because one injection is enough for four times of light irradiation.
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