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Abstract #3213

Frequency-dependent Correlation between Mechanical and Structural Properties of the Human Brain

Suhao Qiu1, Linghan Kong1, Runke Wang1, and Yuan Feng1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China

Synopsis

The relationship between mechanical properties and microscopic structures of brain is of interest to both neuroscience and clinical communities. Using magnetic resonance elastography (MRE), we proposed and verified an empirical model to establish a linear correlation between shifted apparent diffusion coefficient (sADC) and shear modulus. A total of 43 healthy volunteers were included for MRE and diffusion weighted imaging (DWI) scanning. Results demonstrated that, in the parietal lobe, a strong correlation exists between shear modulus and sADC.

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Keywords