Development of quantitative QC methods for prostate DWI is important in clinical practice, necessitating reliable estimates of spatially heterogenous noise. In data obtained at 3T with the use of an endo-rectal coil, we use raw noise measurements to simulate pure-noise k-space datasets that are post-processed to yield noise maps. Good agreement is found between noise levels measured from noise maps in the central prostate and the estimates of noise produced from the anterior rectal ROIs in high TE / high b-value DWI. Thus, noise can be estimated from an anterior rectum region when the endo-rectal coil is used.
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