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Abstract #3333

Maternal Obesity Alters Neuro-Connectivity in Baboon Offspring

Wei D Zhang1, Peter T Fox 1, Hillary F Huber2, Peter William Nathanielsz3, and Geoffrey D Clarke4
1Research Imaging Institute, UT Health San Antonio, San Antonio, TX, United States, 2Texas Pregnancy & Life-Course Health Research Center, Texas Biomedical Research Institute, San Antonio, TX, United States, 3Animal Science, University of Wyoming, Laramie, WY, United States, 4Research Imaging Insitute, UT Health San Antonio, San Antonio, TX, United States


Maternal obesity status was found to affect neural functional connectivity of adult offspring in in a baboon model. Significant differences in connectivity between offspring of obese mothers and age/sex matched controls were found in regions of the left temporal lobe and frontal lobe using rs-fMRI.

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