Abstract #3365

Lung perfusion at 0.55T using ASL: Feasibility and Initial Results

Ziwei Zhao¹, Nam G. Lee², Sophia X. Cui³, and Krishna S. Nayak^1,2

¹Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States, ²Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, ³Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States

Synopsis

Lung perfusion is challenging because of the complex anatomy and pulsatile blood flow. At 1.5T and 3T, a major challenge is the low signal from parenchyma due to the short T2*. Here, we demonstrate feasibility of lung ASL perfusion imaging on a high-performance 0.55T system. Experiments were performed using FAIR labeling with snapshot bSSFP imaging and quantified using Buxton’s GKM. In four healthy volunteers, pulmonary blood flow (PBF) ranges from 0.62 to 0.99 ml-blood/ml-tissue/min, which are within the expected range (0.51 to 1.52 ml/ml/min) and agree with the total average PBF estimated by a phase contrast method.

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