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Abstract #3372

Estimation of Lung Parenchyma Transverse Relaxation Rates at 0.55 Tesla

Bochao Li1, Nam Gyun Lee1, and Krishna Shrinivas Nayak1,2
1Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, 2Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

Lung MRI with excellent image quality has been demonstrated at 0.55T, largely due to reduced susceptibility effects. Here, we present joint estimation of lung parenchyma transverse relaxation rates $$$R_{2}$$$, $$$R_{2}^{\prime}$$$, and off-resonance $$$\Delta f$$$. A custom echo-shifted turbo spin echo (TSE) pulse sequence with ECG triggering and breath hold was performed in 4 healthy volunteers, resulting in the mean $$$R_{2}$$$ of 23.4s-1, $$$R_{2}^{\prime}$$$ of 53.9s-1, and $$$\Delta f$$$ of 45.7Hz. This work demonstrates the feasibility of echo-shifted TSE for the estimation of three parameters of interest in lung MRI, and confirms prior measurements made with separate pulse sequences.

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