Nonalcoholic fatty liver disease (NAFLD) is a common liver disorder that is the first step in a cascade of liver damage. Hence, there is a clinical need for non-invasive, early identification of patients. We hypothesize that the intra-hepatocyte fatty acid composition provides information about NAFLD. To test this, the 1H-MRS spectra of fatty acids in the livers of healthy and NAFLD mice were measured at 9.4 T. Exploratory data analysis shows the spectra can be correctly classified with SVMs. Our results open an opportunity to develop a non-invasive tool for staging NAFLD patients without the need of liver biopsy.
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