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Abstract #3388

Reproducibility of Functional Lung Parameters derived from non-contrast enhanced self-gated 2D Ultrashort Echo-Time (UTE) in Healthy Subjects

Bingjie Yang1, Patrick Metze1, Anke Balasch1, Kilian Stumpf1, Meinrad Beer2, Wolfgang Rottbauer1, and Volker Rasche1
1Department of Internal Medicine II, Ulm University Medical Center, Ulm, Germany, 2Department of Radiology, Ulm University Medical Center, Ulm, Germany


MRI lung imaging is challenging due to cardiac and respiratory motion and the short T2*. In this study the reproducibility of lung function parameters derived from data acquired either from a breath-hold or free-breathing tiny golden angle UTE (2D tyGA UTE) technique have been assessed. Inter-observer and inter-measurement reproducibility was assessed for different lung parameters including lung density and qualitative and quantitative ventilation and perfusion. In general, a very good inter-observer reproducibility and superior reproducibility of the lung function parameters was observed for the free-breathing approach.

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