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Abstract #3387

3D multi-echo GRE MRI of the whole liver: First experiences of a volumetric segment-by-segment R2* analysis

Arthur Peter Wunderlich1,2, Holger Cario3, Stephan Kannengießer4, Veronika Grunau1, Michael Götz1,2, Meinrad Beer1, and Stefan Andreas Schmidt1
1Dept. for Diagnostic and Interventional Radiology, Ulm University, Medical Center, Ulm, Germany, 2Section for Experimental Radiology, Ulm University, Medical Center, Ulm, Germany, 3Clinic of Pediatrics and Adolescent Medicine, Ulm University, Medical Center, Ulm, Germany, 4MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany


Purpose: To test liver segmentation of 3D-multi-gradient-echo MRI data and segmental R2* evaluation.

Methods: 44 patients examined by multi-gradient-echo MRI underwent semiautomatic liver segmentation and subdivision into nine segments. Segmental R2* values were analyzed in all patients together and in patient subgroups.

Results: R2* was lowest in segment 1 (S1), differences to S1 were significant for S3, S5 and S6, highly significant to S2 and S7. Patients with high average R2* showed also significant differences to S1 in some segments.

Conclusions: Inhomogeneity of hepatic iron distribution was found. Low R2* in S1 may be explained by its special vascular supply.

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