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Abstract #3401

Improving cortical bone imaging using a novel Flexible Ultra Short Echo time (FUSE) sequence for optimal synthetic CT generation

Lumeng Cui1, Emily J. McWalter1,2, Gerald R. Moran3, and Niranjan Venugopal4
1Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, 2Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, 3Research Collaboration Manager, Siemens Healthcare Limited, Oakville, ON, Canada, 4Department of Radiology, University of Manitoba, Winnipeg, MB, Canada


Ultrashort echo time (UTE) pulse sequences are used in synthetic computed tomography (sCT) generation for MR-based radiation treatment planning (RTP). This study used a novel Flexible UTE sequence (FUSE) for improving cortical bone imaging. Using a human skull, we applied the optimized UTE acquisition techniques and parameters and verified the improvements in overall image quality of cortical bone in comparison to a product UTE sequence. Also, we have shown the feasibility and potential of our FUSE sequence for generating the sCT data that is clinically equivalent to the traditional CT for RTP.

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