Abstract #3401

Improving cortical bone imaging using a novel Flexible Ultra Short Echo time (FUSE) sequence for optimal synthetic CT generation

Lumeng Cui¹, Emily J. McWalter^1,2, Gerald R. Moran³, and Niranjan Venugopal⁴

¹Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, ²Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, ³Research Collaboration Manager, Siemens Healthcare Limited, Oakville, ON, Canada, ⁴Department of Radiology, University of Manitoba, Winnipeg, MB, Canada

Synopsis

Ultrashort echo time (UTE) pulse sequences are used in synthetic computed tomography (sCT) generation for MR-based radiation treatment planning (RTP). This study used a novel Flexible UTE sequence (FUSE) for improving cortical bone imaging. Using a human skull, we applied the optimized UTE acquisition techniques and parameters and verified the improvements in overall image quality of cortical bone in comparison to a product UTE sequence. Also, we have shown the feasibility and potential of our FUSE sequence for generating the sCT data that is clinically equivalent to the traditional CT for RTP.

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