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Abstract #3411

Test-retest Repeatability of High-resolution Whole-brain DCE-MRI in High-grade Glioma Patients

Zhibo Zhu1, Yannick Bliesener1, Frances Chow2, Jay Acharya3, and Krishna S. Nayak4
1Department Of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States, 2Department of Neurosurgery, University of Southern California, Los Angeles, CA, United States, 3Department of Radiology, University of Southern California, Los Angeles, CA, United States, 4Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

We perform a prospective test-retest repeatability study of one such approach, in patients with high-grade glioma. Two separate scans were performed within 3-7 days apart. Tumor, scalp, normal white matter, pons, cerebellum and muscle regions were segmented manually. The coefficients of variation of median Kt were 50.4% to 66.6% and of median vp were 23.2% to 80.0%, based on our first 5 subjects.

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