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Abstract #3416

Quantitative Susceptibility Mapping for Gold Fiducial Marker Localization in Prostate for MRI-Only Radiation Therapy Treatment Planning

Jie Deng1, Chenyang Shen1, Junjie Wu1, and Steve B Jiang1
1Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, United States


MRI-only simulation permits superior soft tissue contrast for tumor tissue characterization and target margin delineation. One bottleneck preventing MRI-only simulation to be widely applied in prostate cancer EBRT is the tedious marker localization process on MR images as compared to that on a CT. The fiducial and calcification on MRI also appear to be similar, which reduces the confidence level of the clinician in fiducial localization, and further increases the time needed. In this study, we developed a framework using quantitative susceptibility mapping to automatically identify the fiducial markers based on phase information of gradient-echo MRI.

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