Advanced diffusion MRI models are being explored to study the complex microstructure of the brain with higher accuracy. However, these techniques require long acquisition times. Simultaneous multi-slice (SMS) accelerates data acquisition by exciting multiple image slices simultaneously and separating the overlapping slices using a mathematical model. However, SMS acceleration introduces increased noise in reconstructed images and crosstalk between simultaneously excited slices. These compounded effects from SMS acceleration could affect tissue microstructure parameters derived from advanced diffusion MRI models.
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