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Abstract #3491

Characterizing Corticobulbar and Corticospinal Tracts into the Cervical Spinal Cord with Sub-Millimeter Isotropic DTI

Bruce Iain1, Yixin Ma1, and Allen Song1
1Brain Imaging and Analysis Center, Duke University, Durham, NC, United States


An ability to characterize the corticobulbar and corticospinal tracts from the motor cortex into the spinal cord with diffusion tensor imaging remains a challenge due to limiting factors such as achievable spatial resolutions, spatial coverages, and signal-to-noise ratio in the spinal cord. By extending the field-of-view through a combination of sub-millimeter isotropic axial and sagittal acquisitions, this study presents a technique to delineate the complete pyramidal tracts with data acquired at a sufficient spatial resolution to resolve intricate structural details such as the pyramidal decussation. Such a delineation can facilitate placement of spinal cord stimulation electrodes for movement disorder treatments.

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