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Abstract #3508

Volumetric patch-based image reconstruction for enhancing hyperpolarized 13C MRI with hybrid image guidance

Sung-Han Lin1, Junjie Ma1, and JaeMo Park1,2,3
1Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, 2Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Electrical and Computer Engineering, UT Dallas, Richardson, TX, United States


This study presents a volumetric extension of the previously proposed patch-based algorithm for enhancing spatial resolution of 13C MRI. Feasibility of integrating structural and perfusion images as guidance for the patch-based reconstruction is also demonstrated with a digital phantom. The performance of the method was further tested for a hyperpolarized 13C lactate brain image using hybrid probability maps, created from T1-weighted 1H MRI and perfusion images.

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