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Abstract #3547

Effect of Static Background Gradients on Diffusion Contrast Near Large Metallic Implants

Philip Kenneth Lee1,2, Daehyun Yoon2, and Brian Andrew Hargreaves1,2,3
1Electrical Engineering, Stanford University, Stanford, CA, United States, 2Radiology, Stanford University, Stanford, CA, United States, 3Bioengineering, Stanford University, Stanford, CA, United States

Synopsis

Metallic implants create severe off-resonance adjacent to the implant, in the range of 2-20 kHz at 3T. The off-resonance pattern creates a static, “always on” background gradient with unknown amplitude and polarity. Static non-linear background gradients are a known source of local encoding errors, but their effect on diffusion contrast near implants has not yet been evaluated. Static background gradients are distinct from diffusion gradient non-linearities, which affect the achieved b-value if sufficiently large. We apply theoretical results and phantom experiments to evaluate two different diffusion encoding schemes and evaluate the effect of metal-induced off-resonance on ADC quantification.

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