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Abstract #3548

NOVEL POINT-OF-CARE MAGNETIC RESONANCE TECHNOLOGY TO MEASURE LIVER FAT: PHANTOM AND FIRST-IN-HUMAN PILOT STUDY

Mark Barahman1, Eduardo Grunvald2, Pablo J Prado3, Alejandro Bussandri3, Walter C Henderson1, Tanya Wolfson1, Kathryn J Fowler1, and Claude B Sirlin1
1Radiology, UCSD, San Diego, CA, United States, 2Internal Medicine, UCSD, San Diego, CA, United States, 3Livivos Inc, San Diego, CA, United States

Synopsis

LiverScope® is a novel point-of-care (POC) NMR technology for liver fat quantification.

· POC NMR PDFF agreed closely with ground-truth PDFF values in commercial PDFF phantoms (R2 = 0.99)

· POC NMR was feasible in an outpatient clinic, had no demonstrated adverse events, and agreed closely with contemporaneous MRI-PDFF reference standard values (R2 = 0.94) in human adults with obesity and at risk for NAFLD:

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