Abstract #3548

NOVEL POINT-OF-CARE MAGNETIC RESONANCE TECHNOLOGY TO MEASURE LIVER FAT: PHANTOM AND FIRST-IN-HUMAN PILOT STUDY

Mark Barahman¹, Eduardo Grunvald², Pablo J Prado³, Alejandro Bussandri³, Walter C Henderson¹, Tanya Wolfson¹, Kathryn J Fowler¹, and Claude B Sirlin¹

¹Radiology, UCSD, San Diego, CA, United States, ²Internal Medicine, UCSD, San Diego, CA, United States, ³Livivos Inc, San Diego, CA, United States

Synopsis

LiverScope® is a novel point-of-care (POC) NMR technology for liver fat quantification.

· POC NMR PDFF agreed closely with ground-truth PDFF values in commercial PDFF phantoms (R² = 0.99)

· POC NMR was feasible in an outpatient clinic, had no demonstrated adverse events, and agreed closely with contemporaneous MRI-PDFF reference standard values (R² = 0.94) in human adults with obesity and at risk for NAFLD:

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