Modeling diffusion that incorporates the microscopic partially absorbing wall is a more realistic description compared to the standard Bloch equation based two-site model with exchange. The resulting signal equations are more complex and involve working in the Laplace domain. Here, we demonstrate that the increased spatial relevance of the partially absorbing wall model does not improve fitting in our AML model treated with cisplatin for cell death. In fact, the partially absorbing wall model fits and parameters are poorer. Therefore, extracting diffusion parameters from the Bloch equation based two-site exchange model is sufficient for our diffusion MRI datasets.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords