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Abstract #3574

Restoration of corrupted 13C MR spectroscopy with signal overflow

Leon Sergey Khalyavin1 and Jae Mo Park1
1University of Texas at Dallas, Richardson, TX, United States


This study aims to reconstruct 13C spectrum from FID that is corrupted by signal overflow. As the corruption often occurs in the beginning of the FID, an uncorrupted section can be reconstructed as a time-delayed version of the FID. The T2*, M0, and frequency of metabolite peaks can be calculated from the reconstructed spectrum of the uncorrupted FID signal. Since the T2* is an innate property of the compound, it can be used to extrapolate the M0 of the original signal using a mono-exponential function for each peak. The method was tested with dynamic hyperpolarized 13C MRS data.

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