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Abstract #3606

Altered Brain Regional Homogeneity at Resting-State in Spinocerebellar Ataxia Type 3 Patients

Bing Liu1,2, Linwei Zhang3, Wenwen Gao1, Lei Du1, Aocai Yang1, Yue Chen1, Yige Wang1, Xiuxiu Liu1, Kuan Lv1, and Guolin Ma1
1Department of Radiology, China Japan Friendship Hospital, Beijing, China, 2Graduate School of Peking Union Medical College, Beijing, China, 3Department of Neurology, China Japan Friendship Hospital, Beijing, China


To explore the neurofunctional change in spinocerebellar ataxia type 3 patients, regional homogeneity values were analyzed from this resting-state functional magnetic imaging study. The altered brain regional homogeneity mainly appeared in the left cerebellum and right cerebrum. And positive correlations were shown between regional homogeneity values for the right cerebrum and the clinical ataxia scores.

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