Abstract #3606

Altered Brain Regional Homogeneity at Resting-State in Spinocerebellar Ataxia Type 3 Patients

Bing Liu^1,2, Linwei Zhang³, Wenwen Gao¹, Lei Du¹, Aocai Yang¹, Yue Chen¹, Yige Wang¹, Xiuxiu Liu¹, Kuan Lv¹, and Guolin Ma¹

¹Department of Radiology, China Japan Friendship Hospital, Beijing, China, ²Graduate School of Peking Union Medical College, Beijing, China, ³Department of Neurology, China Japan Friendship Hospital, Beijing, China

Synopsis

To explore the neurofunctional change in spinocerebellar ataxia type 3 patients, regional homogeneity values were analyzed from this resting-state functional magnetic imaging study. The altered brain regional homogeneity mainly appeared in the left cerebellum and right cerebrum. And positive correlations were shown between regional homogeneity values for the right cerebrum and the clinical ataxia scores.

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