This study used a novel statistical analysis-2x2 interaction effect to differentiate OCD patients from healthy controls in both adolescents and adults. We analyzed a classical index-low frequency fluctuation amplitude(ALFF) and drew a convincing conclusion that some regions had a correlation with people in different age and symptoms in OCD patients. Originally, we proposed a novel strategy of dALFF which allows estimating dynamics of intrinsic brain activity with patients. Compared to static indexes, dynamic indexes might be used as a powerful supplement differentiating patients from different age, helping us obtain a more comprehensive understanding of neural activity.
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