The purpose of this study is to evaluate the effects of midazolam on resting-state networks in common marmosets. Functional data were collected using a 9.4 T MRI system in the sedative condition with midazolam, the awake condition as a positive control, and the anesthetic condition with isoflurane as a negative control. Independent component analysis and functional connectivity analysis were performed. These results were apparently altered by isoflurane from awake condition, but not largely by midazolam. These results in midazolam were different from a previous report in humans and it may cause different effects of midazolam in human and nonhuman primates.
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