Abstract #3627

Diffusion–Based Virtual MR Elastography of the asymmetric features of neonatal white matter

Yao Ge¹, Xianjun Li², Congcong Liu², Miaomiao Wang², Linlin Zhu², Pengxuan Bai², Na Zhang², Yuying Feng², and Jian Yang²

¹Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, xi’an, China, ²Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, xi'an, China

Synopsis

Exploring the asymmetry of the neonatal brain white matter is of great significance for exploring the developmental rules and disease pathogenesis. Virtual MR elastography (VMRE) as a non-invasive technique has also enabled to relate maturation of cerebral structures to neonatal neurodevelopment in addition to conventional techniques.This study aims to explore the capability of diffusion–based VMRE in the characterization of the asymmetric of the neonatal white matter stiffness.The stiffness of neonatal white matter existed asymmetry, and there was a correlation between it and PMA. VMRE may enable to explore the developing brain at several levels.

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