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Abstract #3626

Radiomics based characterization of peritumoral edema segmented from DCE MRI to differentiate glioblastoma from solitary brain metastasis

Suhail Parvaze P1, Rakesh K Gupta2, Rupsa Bhattacharjee3, Anup Singh4, Rakesh Kumar Singh5, Gaurav Khanna6, Amal Roy Chaudhary7, Rana Patir8, Sandeep Vaishya8, Jaladhar Neelavalli 9, and Tejas Shah9
1Philips Innovation Campus, Bangalore, India, 2Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurugram, India, 3Indian Institute of Technology Delhi, Delhi, India, 4Department of Biomedical Engineering, Indian Institute of Technology Delhi, Delhi, India, 5Fortis Memorial Research Institute, Gurugram, India, 6SRL Diagnostics, Fortis Memorial Research Institute, Gurugram, India, 7Radiation Oncology, Fortis Memorial Research Institute, Gurugram, India, 8Department of Neurosurgery, Fortis Memorial Research Institute, Gurugram, India, 9BIU, Philips Innovation Campus, Bangalore, India

Synopsis

Edema in GB is characterized by the presence of tumor cells infiltration as compared to brain metastasis with only pure edema. Radiomics features extracted using FLAIR images in GB and BM are found to be exhibiting variation in some of the entropy and non-uniformity-based features, which could be used as signature to differentiate GB from brain metastasis.

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