Abstract #3649

Quantification of fine CSF dynamics using Intra-Voxel Incoherent Motion (IVIM) MRI

Shigeki Yamada^1,2, Yoshiyuki Watanabe³, Tomohito Otani⁴, Shinnosuke Hiratsuka³, Masahiro Yoshimura³, Naoki Takeishi⁴, Shigeo Wada⁴, Marie Oshima², and Kazuhiko Nozaki¹

¹Neurosurgery, Shiga University of Medical Science, Otsu, Japan, ²Interfaculty Initiative in Information Studies, Institute of Industrial Science, The University of Tokyo, Tokyo, Japan, ³Radiology, Shiga University of Medical Science, Otsu, Japan, ⁴Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Osaka, Japan

Synopsis

The f value calculated by the Intra-Voxel Incoherent Motion (IVIM) MRI was was high in the areas where the CSF flow was reported to be fast, specifically in the cerebral aqueduct and subarachnoid spaces around the major intracranial arteries. Therefore, f value was considered to reflect flow velocity of CSF, regardless of its direction. The mean f values in the whole lateral ventricles, anterior part of the third ventricle, ambient cisterns, central sulci, and marginal sulci were significantly lower and that in the foramina of Luschka was significantly higher among 28 iNPH patients, compared with 57 healthy volunteers.

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