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Abstract #3649

Quantification of fine CSF dynamics using Intra-Voxel Incoherent Motion (IVIM) MRI

Shigeki Yamada1,2, Yoshiyuki Watanabe3, Tomohito Otani4, Shinnosuke Hiratsuka3, Masahiro Yoshimura3, Naoki Takeishi4, Shigeo Wada4, Marie Oshima2, and Kazuhiko Nozaki1
1Neurosurgery, Shiga University of Medical Science, Otsu, Japan, 2Interfaculty Initiative in Information Studies, Institute of Industrial Science, The University of Tokyo, Tokyo, Japan, 3Radiology, Shiga University of Medical Science, Otsu, Japan, 4Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Osaka, Japan


The f value calculated by the Intra-Voxel Incoherent Motion (IVIM) MRI was was high in the areas where the CSF flow was reported to be fast, specifically in the cerebral aqueduct and subarachnoid spaces around the major intracranial arteries. Therefore, f value was considered to reflect flow velocity of CSF, regardless of its direction. The mean f values in the whole lateral ventricles, anterior part of the third ventricle, ambient cisterns, central sulci, and marginal sulci were significantly lower and that in the foramina of Luschka was significantly higher among 28 iNPH patients, compared with 57 healthy volunteers.

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