Early evaluation and treatment of delayed graft function due to renal cold ischemia reperfusion injury has important clinical significance for prolonging donor kidney preservation times and improving the survival rates of allografts. Arterial spin labeling (ASL) and diffusion-weighted imaging (DWI) have been accepted for microstructure change evaluations of renal function. In this study, transplant recipients were collected for fMRI examination at 14d, 30d and 90d after transplantation. The parameters were compared to evaluate renal microstructure changes among different time points. The results showed ASL and DWI can reflect longitudinal changes of diffusion and perfusion properties for allografts after kidney transplantation .