Differentiating Benign from Malignant Renal Cystic Masses Using Continuous-time Random-walk diffusion model
Xiaojun Yang1, Xiaohui Duan1, Mengzhu Wang2, Xu Yan2, Lingjie Yang1, Weike Zeng1, Wei Jiang1, Yaojun Hu1, Guang Yang3, and Jun Shen1
1Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China, 22MR Scientific Marketing, Siemens Healthineers, Guangzhou, China, 3Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, China
This study evaluated whether continuous-time random-walk (CTRW) diffusion model could be used to distinguish benign from malignant renal tumors, as well as compared the diagnostic effectiveness between the diffusion parameters of CTRW and apparent dispersion coefficient (ADC). The results demonstrated that CTRW diffusion model as a new noninvasive MR technique, was able to differentiate benign from malignant renal masses in vivo, and further improve the diagnostic efficiency of renal malignant masses compared with conventional diffusion imaging.
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