Abstract #3663

Differentiating Benign from Malignant Renal Cystic Masses Using Continuous-time Random-walk diffusion model

Xiaojun Yang¹, Xiaohui Duan¹, Mengzhu Wang², Xu Yan², Lingjie Yang¹, Weike Zeng¹, Wei Jiang¹, Yaojun Hu¹, Guang Yang³, and Jun Shen¹

¹Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China, ²2MR Scientific Marketing, Siemens Healthineers, Guangzhou, China, ³Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, China

Synopsis

This study evaluated whether continuous-time random-walk (CTRW) diffusion model could be used to distinguish benign from malignant renal tumors, as well as compared the diagnostic effectiveness between the diffusion parameters of CTRW and apparent dispersion coefficient (ADC). The results demonstrated that CTRW diffusion model as a new noninvasive MR technique, was able to differentiate benign from malignant renal masses in vivo, and further improve the diagnostic efficiency of renal malignant masses compared with conventional diffusion imaging.

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