This multi-center retrospective study performed automatic segmentation of bladder cancer (BC) on MRI with a convolutional neural network and evaluated the reproducibility of radiomics features. Of the total 170 patients, 140 were used to train our U-net model and 30 were used to evaluate the segmentation performance of the model. Our U-net model achieved a median Dice similarity coefficient of 0.811 in the test dataset and most of the automatically extracted radiomics features showed high reproducibility (median intraclass correlation coefficient: 0.83-0.86). Our model would lead to efficient medical image analysis of BC using the radiomics approach.
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