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Abstract #3693

Differentiation between benign and malignant breast masses using 3D amide proton transfer weighted imaging and dynamic contrast-enhanced MRI

Ruhua Wang1, Yan Zhang1, Liangjie Lin2, and Jingliang Cheng1
1Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2Philips Healthcare, Beijing, China


This study evaluated the diagnostic value of dynamic contrast-enhanced MRI (DCE-MRI) combined with 3D amide proton transfer weighted imaging (APTWI) for differentiation between benign and malignant breast masses. Results indicated the quantitative MTRasym(3.5 ppm) value calculated by APTWI was significantly different between benign and malignant lesions, and the combination of APTWI and DCE-MRI improves the diagnostic performance for discriminating benign and malignant breast masses, especially category 4 masses.

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