Abstract #3693

Differentiation between benign and malignant breast masses using 3D amide proton transfer weighted imaging and dynamic contrast-enhanced MRI

Ruhua Wang¹, Yan Zhang¹, Liangjie Lin², and Jingliang Cheng¹

¹Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²Philips Healthcare, Beijing, China

Synopsis

This study evaluated the diagnostic value of dynamic contrast-enhanced MRI (DCE-MRI) combined with 3D amide proton transfer weighted imaging (APTWI) for differentiation between benign and malignant breast masses. Results indicated the quantitative MTRasym(3.5 ppm) value calculated by APTWI was significantly different between benign and malignant lesions, and the combination of APTWI and DCE-MRI improves the diagnostic performance for discriminating benign and malignant breast masses, especially category 4 masses.

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