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Abstract #3694

3D Amide Proton Transfer-weighted Imaging In Evaluation Of Breast Lesions: Comparison With Diffusion-weighted Imaging

Ruhua Wang1, Yan Zhang1, Liangjie Lin2, and Jingliang Cheng1
1Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2Philips Healthcare, Beijing, China


This purpose of this study is to investigate the value of 3D APTWI and evaluate the diagnostic efficacy of its combination with DWI for discriminating breast benign from malignant lesions. Results showed the MTRasym(3.5 ppm) value calculated by APTWI for malignant breast lesions were significantly lower than those of benign lesions, and APTWI combined with DWI obtained a better diagnostic performance than the single method. Therefore, APTWI is a novel technique, which can be used to differentiate breast benign from malignant lesions noninvasively.

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