This purpose of this study is to investigate the value of 3D APTWI and evaluate the diagnostic efficacy of its combination with DWI for discriminating breast benign from malignant lesions. Results showed the MTRasym(3.5 ppm) value calculated by APTWI for malignant breast lesions were significantly lower than those of benign lesions, and APTWI combined with DWI obtained a better diagnostic performance than the single method. Therefore, APTWI is a novel technique, which can be used to differentiate breast benign from malignant lesions noninvasively.
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