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Abstract #3707

Intravoxel Incoherent Motion (IVIM) DiffusionWeighted imaging in quantitatively evaluation of WT-1 expression in Ovarian Cancer

Jiajun Guo1, Ye Li1, Ailian Liu1, and Yulin Chen1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, Dalian, China


Ovarian cancer (OC) behaves more aggressively and has a worse prognosis than any other cancer involving the female genital tract. WT-1 was significantly upregulated in human OC tissues and closely associated with OC type, grade and FIGO stage. This worked aimed at exploring the value of Intravoxel incoherent motion (IVIM) quantitative parameters for diagnosis of WT-1 positive OC. The results showed that D value provided a promising performance (AUC = 0.740, sensitivity= 88.2%, specificity= 70.6 %) in quantitatively evaluating WT-1 positive OC.

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