This study aimed to compare and analyse the diagnostic value of PI-RADS v2.1 when used with bpMRI versus mpMRI, DWI versus T2WI to detect peripheral-zone prostate cancer (pzPCa) and clinically significant prostate cancer (csPCa). The diagnostic efficiencies of mpMRI and bpMRI as well as DWI and T2WI in pzPCa and csPCa were compared using a PI-RADS score of ≥4 as the positive threshold and pathologic results as the gold standards. MpMRI and bpMRI as well as DWI and T2WI using PI-RADS v2.1 exhibited similar diagnostic efficiency in pzPCa and csPCa, whereas bpMRI demonstrated increased diagnostic specificity compared with mpMRI.
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