Diffusion-weighted imaging (DWI) with shorter echo time (TE) could be exploited to improve diffusion contrast by minimizing T2 shine-through due to longer T2 in normal prostate. However, clinical magnetic resonance imaging (MRI) scanner has limitation in shortening TE in conventional DWI. It would be beneficial to generate additional DWI with short TE from DWIs with two different TE, in addition to short repetition time (TR) which improvement of diffusion contrast has been reported. The synthetic DWI with shorter TR (1000 ms) and TE (1 ms) tended to show better diffusion contrast than real-acquired DWI with conventional TR and TE.
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