DWI is a key component of the prostate MRI examination, but current prostate DWI images acquired with high b-value DWI using SENSE often suffer from increased noise artifacts. We propose to utilize a deep learning constrained Compressed SENSE (CS-AI) for reducing the noise artifacts in single-shot DW-EPI images. CS-AI DWI clearly reduces noise-like artifacts, boosts the overall SNR and significantly improves the accuracy and robustness of ADC values in rapid high b-value prostate DWI compared with conventional SENSE- and CS-DW-EPI, without any penalty for scan parameters.
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