T2-weighted (T2W) imaging is used to depict prostate anatomy. However, T2W imaging with high spatial resolution, which is required by PI-RADSv2, is not always performed because of the long scan time. In this study, we investigated the use of Compressed SENSE AI (CS-AI) reconstruction to accelerate high-resolution T2W imaging of the prostate. The image quality of CS-AI reconstruction, conventional Compressed-SENSE (C-SENSE), and SENSE were compared qualitatively and quantitatively. Clinical cases demonstrated a significant noise reduction in accelerated CS-AI. CS-AI also showed a significantly higher contrast-to-noise ratio in CS-AI compared to SENSE and C-SENSE.